Conditions and vaccines for prevention of common diseases

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Note: The information contained in these pages is intended as a general guide only. Always obtain professional advice about your specific situation.

Vaccines include:

  • Clostridial vaccines prevent mortality against black leg, black disease, tetanus, pulpy kidney and malignant oedema.
  • Vibriovax® protects against campylobacter infection in breeding cows that can cause infertility and abortion.
  • Leptospirosis vaccine protects against abortion, calf deaths and reduces shedding of leptospira bacterium and consequently the risk of human infection.
  • Pestigard® vaccine prevents reproductive wastage and mortalities caused by mucosal disease or pestivirus.
  • Piliguard® vaccine prevents pinkeye caused by Moraxella bovis.
  • Botulism vaccines protect against mortality caused by Clostridium botulinum Types C and D

This table is used to help identify conditions and vaccines used to prevent the development of common diseases that can lead to significant economic loss when left untreated.

Clostridial disease

Conditions when likely to occur



Penetrating wound including marking wounds

  • Ultravac®5in1
  • Websters®5in1vaccine for cattle and sheep
  • Websters®5in1vaccine with vitamin B12 for cattle and sheep
  • Websters®low volume 5in1vaccine for cattle and sheep
  • Tasvax®5in1
  • Tasvax®8in1 which include additional strains of C. perfrinengens and C. haemolyticum

Black leg

Muscle bruising, growing animals

Black disease

Liver fluke infestation

Malignant oedema


Pulpy kidney

Lush pasture, heavy grain feeding, change feed


Phosphorus and protein deficiency which causes carcase and bone chewing. This can be habit forming behaviour and animals can continue to chew bones even when protein and phosphorus are adequate.

  • Websters®low volume bivalent botulinum vaccine for sheep and cattle
  • Ultravc®boulinum vaccine
  • Longrange® botulinum vaccine
  • Singvac®2 year single shot botulinum vaccine for cattle
  • Singvac® 3 year single shot botulinum vaccine for cattle

With all clostridial disease, consider the local risk based on previous local district history and if available property history. Intensification is likely to increase risk of clostridial diseases such as blackleg or pulpy kidney.


Conditions when likely to occur




Venereal infection, likely to occur when cattle (bulls, mated heifers, cows) introduced to breeding herd, particularly from unknown origin.

  • Vibriovax®


Imported cattle or neighbouring cattle likely to introduce disease.

Properties trading cattle in conjunction with a breeding herd are at higher risk.

Cattle have contact with wildlife reservoirs such as feral pigs.

Previous history of leptospirosis in herd.

Cattle have access to wet areas where leptospirosis bacteria survive.

Workers and veterinarians will be at risk if handling cattle shedding bacterium.

  • Cattlevax®LC 7in1
  • Leptoshield®
  • LeptoVax®
  • Ultravac®7in1
  • Websters®Clepto-7


Mucosal disease (bovine pestivirus or BVDV - bovine viral diarrhoea virus)

Close contact between cattle.

Cattle shedding virus introduced to herd, or persistently infected cattle already present in herd infect susceptible cattle in early pregnancy.

Breeding herds are most at risk if other cattle are brought onto property or they have access to other cattle.

  • Pestigard®vaccine


Young cattle especially in close contact such as around watering points and dusty yards or supplementary feeding. Flies and dust are likely to spread the conditions and cattle in poor condition are more susceptible.

Introduced cattle or herds that trade a lot of cattle are likely to be at more risk, especially if they have no previous exposure.

  • Coopers® Piliguard®

Important considerations when vaccinating cattle:

  • Follow the manufacturer’s instructions closely.
  • Store and handle vaccines correctly to ensure the effectiveness of the vaccine is not reduced.
  • Carefully adhere to safety precautions for workers handling vaccines and associated equipment.
  • Dispose of used equipment safely, avoiding environmental contamination.
  • To optimise the immunity gained ensure animals are in good health.
  • Full protection does not occur until up to four weeks after the initial doses of the vaccine.